Depigmentation therapies in vitiligo
نویسندگان
چکیده
منابع مشابه
Depigmentation therapies for normal skin in vitiligo universalis.
If vitiligo involves most of the body, it might be easier to depigment the normal remaining skin rather than to attempt repigmentation. We reviewed the literature to date regarding available therapies for depigmenting the normal skin in vitiligo universalis. Our review revealed that the threshold regarding what percentage of body surface area qualifies as depigmentation is variable among practi...
متن کاملCCL22 to activate Treg migration and suppress depigmentation in vitiligo
In vitiligo, gradual cutaneous depigmentation and cytotoxic T-cell activity against melanocytes are accompanied by a paucity of regulatory T cells (Tregs) in vitiligo patient skin, indicating that autoimmune responses are not adequately held in check. Thus, we sought a means to repopulate patient skin with Tregs. We hypothesized that enhanced expression of CCL22 can promote Treg skin homing to ...
متن کاملImmunological basis of melanoma-associated vitiligo-like depigmentation.
Vitiligo is a skin condition characterized by white, hypopigmented macules. Melanocyte loss is a feature of the disease, and it has been hypothesized that an autoimmune mechanism could be responsible for the depigmentation. Melanoma is a malignancy that develops in melanocytes; if not detected and treated early, it is often deadly. Leukoderma, a condition characterized by depigmentation of the ...
متن کاملGenital vitiligo-like depigmentation following use of imiquimod 5% cream.
342 d o i : 10.84/ejd .208.0402 Most authors recommend a quick freeze and slow thaw method of tissue destruction. Slow cooling produces extracellular ice, but this is not as damaging as rapid cooling that produces intracellular ice formation. With slow thawing, an increased concentration of electrolytes and recrystallization occurs, which is also damaging to cells. Thus the rate of rewarming, o...
متن کاملUpdate on skin repigmentation therapies in vitiligo.
Treatment for vitiligo is difficult and prolonged. Nevertheless, at present considerable knowledge accumulated during several decades on the pathogenic mechanisms, revealed important clues for designing new strategies to improve vitiligo depigmentation. With available medical therapies, high repigmentation percentages mostly on facial and neck lesions are achieved, although they are less effect...
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ژورنال
عنوان ژورنال: Indian Journal of Dermatology, Venereology, and Leprology
سال: 2012
ISSN: 0378-6323
DOI: 10.4103/0378-6323.90946